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Protein C

April 16, 2010 by Staff  
Filed under Health Conditions / Ailments

Protein C is a protein that in humans is encoded by the PROC gene. Protein C is a major physiological anticoagulant. It is a vitamin K-dependent serine protease enzyme (EC 3.4.21.69) that is activated by thrombin into activated protein C (APC). The activated form (with protein S and phospholipid as a cofactor) degrades Factor Va and Factor VIIIa. It should not be confused with C peptide or c-reactive protein or protein kinase C.

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