Leukoplakia

Leukoplakia is adherent white patches on the mucous membranes of the oral cavity, including the tongue. The clinical appearance is highly variable. Leukoplakia is not a specific disease entity, but is diagnosis of exclusion. It must be distinguished from diseases that may cause similar white lesions, such as candidiasis or lichen planus.

Epstein Barr Virus

The Epstein-Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a cancer causing virus of the herpes family, which includes herpes simplex virus 1 and 2, and is one of the most common viruses in humans. Epstein-Barr virus occurs worldwide. It is known to cause infectious mononucleosis, is implicated in the causation of Burkitt’s lymphoma and Nasopharyngeal carcinoma, and is suspected to have a role in the pathogenesis of chronic fatigue syndrome.