Protein C

Protein C is a protein that in humans is encoded by the PROC gene. Protein C is a major physiological anticoagulant. It is a vitamin K-dependent serine protease enzyme (EC 3.4.21.69) that is activated by thrombin into activated protein C (APC). The activated form (with protein S and phospholipid as a cofactor) degrades Factor Va and Factor VIIIa. It should not be confused with C peptide or c-reactive protein or protein kinase C.

Deep Vein Thrombosis

In medicine, deep vein thrombosis (also known as deep-vein thrombosis or deep venous thrombosis and usually abbreviated as DVT) is the formation of a blood clot (“thrombus”) in a deep vein. It is a form of thrombophlebitis (inflammation of a vein with clot formation).